Basal Patologi KU - BAD, BID and PUMA proteins shift the balance between the pro-apoptotic and anti-apoptotic family members by neutralizing the actions of anti-apoptotic proteins like BCL2 and BCL-XL, thereby promoting
Phylogenetically Distant Viruses Use the Same BH3-Only Protein Puma to Trigger Bax/Bak-Dependent Apoptosis of Infected Mouse and Human Cells | PLOS ONE
![Phosphorylation of Puma modulates its apoptotic function by regulating protein stability | Cell Death & Disease Phosphorylation of Puma modulates its apoptotic function by regulating protein stability | Cell Death & Disease](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fcddis.2010.38/MediaObjects/41419_2010_Article_BFcddis201038_Fig1_HTML.jpg)
Phosphorylation of Puma modulates its apoptotic function by regulating protein stability | Cell Death & Disease
![Schematic diagram of p53 and PUMA regulation of apoptosis following... | Download Scientific Diagram Schematic diagram of p53 and PUMA regulation of apoptosis following... | Download Scientific Diagram](https://www.researchgate.net/publication/224910068/figure/fig11/AS:667076452683790@1536054828431/Schematic-diagram-of-p53-and-PUMA-regulation-of-apoptosis-following-cisplatin-treatment.png)
Schematic diagram of p53 and PUMA regulation of apoptosis following... | Download Scientific Diagram
![Slug mediates nasopharyngeal carcinoma radioresistance via downregulation of PUMA in a p53-dependent and -independent manner Slug mediates nasopharyngeal carcinoma radioresistance via downregulation of PUMA in a p53-dependent and -independent manner](https://www.spandidos-publications.com/article_images/or/33/5/OR-33-05-2631-g03.jpg)
Slug mediates nasopharyngeal carcinoma radioresistance via downregulation of PUMA in a p53-dependent and -independent manner
![ART increases PUMA protein level. PANC-1 (A), BxPC-3 (B), and HCT116... | Download Scientific Diagram ART increases PUMA protein level. PANC-1 (A), BxPC-3 (B), and HCT116... | Download Scientific Diagram](https://www.researchgate.net/publication/321702205/figure/fig5/AS:569629856759813@1512821749535/ART-increases-PUMA-protein-level-PANC-1-A-BxPC-3-B-and-HCT116-C-cells-were.png)
ART increases PUMA protein level. PANC-1 (A), BxPC-3 (B), and HCT116... | Download Scientific Diagram
![Recombinant Human BCL2 binding component 3 (PUMA), transfected HEK293 cell culture supernatant Protein [230-20081-200] Recombinant Human BCL2 binding component 3 (PUMA), transfected HEK293 cell culture supernatant Protein [230-20081-200]](http://www.raybiotech.com/images/detailed/63/Protein_button.gif)
Recombinant Human BCL2 binding component 3 (PUMA), transfected HEK293 cell culture supernatant Protein [230-20081-200]
![Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-κB cytokine pathway | Journal of Neuroinflammation | Full Text Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-κB cytokine pathway | Journal of Neuroinflammation | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12974-018-1271-9/MediaObjects/12974_2018_1271_Fig4_HTML.png)
Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-κB cytokine pathway | Journal of Neuroinflammation | Full Text
![PUMA gene and protein structure. The human PUMA gene contains three... | Download Scientific Diagram PUMA gene and protein structure. The human PUMA gene contains three... | Download Scientific Diagram](https://www.researchgate.net/publication/26704262/figure/fig2/AS:281230605078530@1444062009141/PUMA-gene-and-protein-structure-The-human-PUMA-gene-contains-three-coding-exons-exons.png)