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Targeting the Kappa Opioid Receptor to Reduce Drug Use and Relapse |  National Institute on Drug Abuse (NIDA)
Targeting the Kappa Opioid Receptor to Reduce Drug Use and Relapse | National Institute on Drug Abuse (NIDA)

Frontiers | Mu Opioid Receptor Heterodimers Emerge as Novel Therapeutic  Targets: Recent Progress and Future Perspective
Frontiers | Mu Opioid Receptor Heterodimers Emerge as Novel Therapeutic Targets: Recent Progress and Future Perspective

Selective kappa opioid antagonists for treatment of addiction, are we there  yet? | Semantic Scholar
Selective kappa opioid antagonists for treatment of addiction, are we there yet? | Semantic Scholar

Study provides clues for designing new anti-addiction medications |  National Institutes of Health (NIH)
Study provides clues for designing new anti-addiction medications | National Institutes of Health (NIH)

Narcotic Addiction in Failed Back Surgery Syndrome - Yuan-Chuan Chen,  Ching-Yi Lee, Shiu-Jau Chen, 2019
Narcotic Addiction in Failed Back Surgery Syndrome - Yuan-Chuan Chen, Ching-Yi Lee, Shiu-Jau Chen, 2019

Kappa opioid receptor signaling in the brain: Circuitry and implications  for treatment - ScienceDirect
Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment - ScienceDirect

Opioid receptors: drivers to addiction? | Nature Reviews Neuroscience
Opioid receptors: drivers to addiction? | Nature Reviews Neuroscience

Frontiers | The Kappa Opioid Receptor: From Addiction to Depression, and  Back
Frontiers | The Kappa Opioid Receptor: From Addiction to Depression, and Back

A systematic review on the kappa opioid receptor and its ligands: New  directions for the treatment of pain, anxiety, depression, and drug abuse -  ScienceDirect
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse - ScienceDirect

Opioid agonists, mixed agonist-antagonists and partial agonists | Osmosis
Opioid agonists, mixed agonist-antagonists and partial agonists | Osmosis

Mixed Kappa/Mu Partial Opioid Agonists as Potential Treatments for Cocaine  Dependence - ScienceDirect
Mixed Kappa/Mu Partial Opioid Agonists as Potential Treatments for Cocaine Dependence - ScienceDirect

Selective kappa opioid antagonists for treatment of addiction, are we there  yet? | Semantic Scholar
Selective kappa opioid antagonists for treatment of addiction, are we there yet? | Semantic Scholar

A unique natural selective kappa-opioid receptor agonist, salvinorin A, and  its roles in human therapeutics - ScienceDirect
A unique natural selective kappa-opioid receptor agonist, salvinorin A, and its roles in human therapeutics - ScienceDirect

Effects of Kappa opioid receptor blockade by LY2444296 HCl, a selective  short-acting antagonist, during chronic extended access cocaine  self-administration and re-exposure in rat | Request PDF
Effects of Kappa opioid receptor blockade by LY2444296 HCl, a selective short-acting antagonist, during chronic extended access cocaine self-administration and re-exposure in rat | Request PDF

κ-opioid receptor - Wikipedia
κ-opioid receptor - Wikipedia

Frontiers | Traumatic Stress-Induced Vulnerability to Addiction: Critical  Role of the Dynorphin/Kappa Opioid Receptor System
Frontiers | Traumatic Stress-Induced Vulnerability to Addiction: Critical Role of the Dynorphin/Kappa Opioid Receptor System

The blocking of kappa‐opioid receptor reverses the changes in dorsolateral  striatum dopamine dynamics during the amphetamine sensitization - Azocar -  2019 - Journal of Neurochemistry - Wiley Online Library
The blocking of kappa‐opioid receptor reverses the changes in dorsolateral striatum dopamine dynamics during the amphetamine sensitization - Azocar - 2019 - Journal of Neurochemistry - Wiley Online Library

κ-opioid receptor - Wikipedia
κ-opioid receptor - Wikipedia

Focusing on the Opioid System for Addiction Biomarker Discovery: Trends in  Molecular Medicine
Focusing on the Opioid System for Addiction Biomarker Discovery: Trends in Molecular Medicine

Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands:  Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience
Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience

Psychoactives | Free Full-Text | The Role of the Dynorphin/Kappa Opioid  Receptor System in the Actions of Alcohol
Psychoactives | Free Full-Text | The Role of the Dynorphin/Kappa Opioid Receptor System in the Actions of Alcohol

Pharmaceuticals | Free Full-Text | Biased, Bitopic, Opioid–Adrenergic  Tethered Compounds May Improve Specificity, Lower Dosage and Enhance Agonist  or Antagonist Function with Reduced Risk of Tolerance and Addiction
Pharmaceuticals | Free Full-Text | Biased, Bitopic, Opioid–Adrenergic Tethered Compounds May Improve Specificity, Lower Dosage and Enhance Agonist or Antagonist Function with Reduced Risk of Tolerance and Addiction

A single, extinction-based treatment with a kappa opioid receptor agonist  elicits a long-term reduction in cocaine relapse | Neuropsychopharmacology
A single, extinction-based treatment with a kappa opioid receptor agonist elicits a long-term reduction in cocaine relapse | Neuropsychopharmacology

Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural  Refinement and Evaluation of CNS Clearance | ACS Chemical Neuroscience
Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural Refinement and Evaluation of CNS Clearance | ACS Chemical Neuroscience

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist  Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical  Neuroscience
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience